Anthelmintic Resistance

Dictyocaulus filaria – A Potential Cause of Coughing Sheep

Dictyocaulus filaria – A potential cause of coughing sheep What is Dicytocaulus filaria? One or two sheep coughing in a flock – particularly a harsh dry cough – could be a sign of Dictyocaulus filaria infection. This is a “lungworm” with the adult worms that measure some 4 – 10cm in length – living in the bronchi and causing bronchitis. Unlike other lungworms in sheep, this lungworm has a direct life cycle with larvae passed in droppings developing into infective larvae on pasture. Other…

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CRO_research&development

The shifting nature of veterinary pharmaceutical R&D delivery…a new niche opportunity

The shifting nature of veterinary pharmaceutical R&D delivery…a new niche opportunity Increasingly, large pharmaceutical companies are evolving their business strategies and are incorporating outsourcing of R&D as a norm. Traditionally, large pharma companies would operate in house R&D activities. Nowadays, a multifaceted approach exists for delivering new technologies incorporating in house R&D activities; use of contract research organisations (CROs); and utilising venture capital funded start-up companies. Why are veterinary pharmaceutical companies moving to favour outsourcing of R&D? Companies are moving…

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Ridgeway Research Ltd | Liver Fluke

Liver Fluke: A further insight into it's effect on livestock.

Liver Fluke: A further insight into it’s effect on livestock. Liver fluke infections cost the UK farming industry an estimated £300 million per year, through animal death, or decreased productivity in chronically infected animals that may show no obvious signs of disease. At Ridgeway Research Ltd we are committed to animal welfare and aiding the scientific understanding of parasite life cycles and their control. At our laboratory we maintain the Liver Fluke life cycle, producing and supplying metacercariae to Universities…

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The rising threat of anthelmintic resistance

The rising threat of anthelmintic resistance An anthelmintic (or wormer) is a drug used to destroy parasitic worms. Anthelmintic resistance (AR) is when worms become able to tolerate an anthelmintic and so survive a dose of a drug that would previously have killed them. The resistant worms pass this ability on to their offspring. And as more and more of the resistant worms survive, the rate at which resistance develops increases. A significant global concern AR is a growing problem…

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